VERTEX PHARMACEUTICALS INC / MA (VRTX) Most Active Options
The 25 most actively traded VERTEX PHARMACEUTICALS INC / MA (VRTX) option contracts at the latest daily snapshot, ranked by volume. Each row shows the contract's price, implied volatility, delta, open interest, and how today's volume compares with its own 30-day average — click a contract to analyze it in the OptiView platform.
Data as of Aug 24, 2026, 3:55 PM ET · OPRA data 15 minutes delayed · For information only — not investment advice.
Most Active VRTX Contracts
| Contract | Expiration | DTE | Last | IV | IV rank (30d) | Delta | Open interest | Volume | vs 30d avg |
|---|---|---|---|---|---|---|---|---|---|
| VRTX $555 call | Sep 18, 2026 | 25d | $12.80 | 26.6% | 28 | 0.48 | — | 295 | 26.6× avg |
| VRTX $500 put | Oct 16, 2026 | 53d | $6.40 | — | 23 | — | 21 | 154 | 30.9× avg |
| VRTX $610 call | Sep 18, 2026 | 25d | $1.74 | — | 21 | — | 9 | 90 | 18.3× avg |
| VRTX $460 put | Sep 25, 2026 | 32d | $0.90 | — | — | — | 0 | 83 | — |
| VRTX $565 call | Sep 18, 2026 | 25d | $9.40 | 27.0% | 29 | 0.38 | — | 72 | 6.5× avg |
| VRTX $470 put | Sep 25, 2026 | 32d | $1.50 | — | — | — | 0 | 70 | — |
| VRTX $430 put | Sep 25, 2026 | 32d | $0.36 | — | — | — | 0 | 67 | — |
| VRTX $440 put | Sep 25, 2026 | 32d | $0.58 | — | 23 | — | 3 | 61 | 5.3× avg |
| VRTX $515 put | Aug 28, 2026 | 4d | $0.60 | — | 14 | — | 1 | 56 | 12.5× avg |
| VRTX $485 put | Sep 4, 2026 | 11d | $0.28 | — | 33 | — | 23 | 52 | 12.7× avg |
| VRTX $502.5 put | Sep 4, 2026 | 11d | $0.83 | — | 9 | — | 5 | 52 | 12.7× avg |
| VRTX $405 put | Oct 2, 2026 | 39d | $0.42 | 500.0% | 100 | 0.00 | 0 | 50 | 5.9× avg |
| VRTX $455 put | Oct 2, 2026 | 39d | $1.46 | — | — | — | 0 | 49 | — |
| VRTX $460 put | Oct 2, 2026 | 39d | $1.40 | — | — | — | 0 | 46 | — |
| VRTX $495 put | Sep 4, 2026 | 11d | $0.50 | — | 18 | — | 18 | 40 | 9.8× avg |
| VRTX $440 put | Dec 18, 2026 | 116d | $5.81 | — | 26 | — | 319 | 40 | 53.9× avg |
| VRTX $482.5 put | Sep 4, 2026 | 11d | $0.18 | — | — | — | 0 | 38 | — |
| VRTX $480 put | Jan 15, 2027 | 144d | $15.00 | — | 42 | — | 61 | 33 | 13.7× avg |
| VRTX $487.5 put | Sep 4, 2026 | 11d | $0.26 | — | — | — | 0 | 30 | — |
| VRTX $495 put | Sep 11, 2026 | 18d | $0.92 | — | 17 | — | 17 | 28 | 6.9× avg |
| VRTX $600 call | Sep 18, 2026 | 25d | $2.66 | — | 10 | — | 61 | 28 | 5.7× avg |
| VRTX $550 put | Sep 18, 2026 | 25d | $16.10 | — | 24 | — | 56 | 28 | 2.2× avg |
| VRTX $550 call | Sep 18, 2026 | 25d | $16.20 | — | 54 | — | 528 | 27 | 7.4× avg |
| VRTX $410 put | Oct 2, 2026 | 39d | $0.20 | — | — | — | 0 | 26 | — |
| VRTX $500 put | Sep 18, 2026 | 25d | $2.60 | — | 10 | — | 288 | 26 | 6.4× avg |
Ranked by volume at the latest daily snapshot. "vs 30d avg" compares today's volume with the contract's own 30-day average.
The most active VRTX contract today is the $555 call expiring in 25 days, with 295 contracts traded. Puts dominate the most-active list (20 of the top 25), showing where trading interest concentrates.
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VRTX Options FAQ
Which VRTX option contract is most active today?
The most traded VRTX contract is the $555 call expiring Sep 18, 2026, with 295 contracts traded as of Aug 24, 2026.
How does OptiView rank the most active VRTX options?
The table lists the 25 VRTX contracts with the highest volume at the latest daily snapshot, alongside price, implied volatility, delta, open interest, and each contract's volume versus its own 30-day average.
Methodology. IV rank compares the current 30-day at-the-money implied volatility with its highest and lowest values over the past 52 weeks. Max pain is the strike that minimizes the total payout to option holders at expiration. The call and put walls are the strikes carrying the largest call and put open interest across all expirations. Net gamma exposure (GEX) is measured from the dealer perspective. All statistics are derived from delayed OPRA options data.
Options trading involves significant risk, and losses can exceed your initial investment. Always consult a licensed financial professional before making investment decisions. OptiView does not provide financial advice; all figures on this page are descriptive statistics, not recommendations.