VERTEX PHARMACEUTICALS INC / MA (VRTX) Most Active Options
The 20 most actively traded VERTEX PHARMACEUTICALS INC / MA (VRTX) option contracts at the latest daily snapshot, ranked by volume. Each row shows the contract's price, implied volatility, delta, open interest, and how today's volume compares with its own 30-day average — click a contract to analyze it in the OptiView platform.
Data as of Jul 10, 2026, 8:00 PM ET · OPRA data 15 minutes delayed · For information only — not investment advice.
Most Active VRTX Contracts
| Contract | Expiration | DTE | Last | IV | IV rank (30d) | Delta | Open interest | Volume | vs 30d avg |
|---|---|---|---|---|---|---|---|---|---|
| VRTX $420 put | Sep 18, 2026 | 70d | $7.05 | 37.7% | 50 | -0.16 | 136 | 450 | 38.1× avg |
| VRTX $440 put | Aug 21, 2026 | 42d | $7.30 | 38.4% | 53 | -0.20 | 14 | 128 | 10.8× avg |
| VRTX $475 put | Jul 17, 2026 | 7d | $3.40 | 33.3% | 32 | -0.30 | 16 | 116 | 8.8× avg |
| VRTX $470 call | Sep 18, 2026 | 70d | $39.30 | 33.0% | 28 | 0.64 | 222 | 67 | 11.9× avg |
| VRTX $485 call | Jul 17, 2026 | 7d | $8.20 | 27.8% | 8 | 0.53 | 62 | 64 | 7.4× avg |
| VRTX $450 put | Jul 17, 2026 | 7d | $0.54 | 36.9% | 7 | -0.06 | 136 | 33 | 10.6× avg |
| VRTX $460 put | Jul 24, 2026 | 14d | $3.37 | 33.6% | 10 | -0.19 | 4 | 32 | 6.0× avg |
| VRTX $495 call | Jul 17, 2026 | 7d | $4.30 | 27.7% | 12 | 0.32 | 31 | 32 | 2.2× avg |
| VRTX $480 put | Jul 17, 2026 | 7d | $5.16 | 27.8% | 9 | -0.37 | 387 | 31 | 2.3× avg |
| VRTX $510 call | Jul 17, 2026 | 7d | $1.40 | 29.3% | 16 | 0.12 | 242 | 31 | 2.1× avg |
| VRTX $500 call | Jul 24, 2026 | 14d | $5.25 | 24.1% | 31 | 0.29 | 2 | 30 | 2.6× avg |
| VRTX $620 call | Jan 15, 2027 | 189d | $13.67 | 35.6% | 45 | 0.23 | 485 | 30 | 7.5× avg |
| VRTX $485 call | Jul 24, 2026 | 14d | $11.30 | 25.0% | 38 | 0.53 | 5 | 28 | 3.7× avg |
| VRTX $455 put | Jul 24, 2026 | 14d | $3.59 | 38.1% | 18 | -0.18 | 1 | 27 | 5.0× avg |
| VRTX $520 call | Jul 24, 2026 | 14d | $2.48 | 33.1% | 22 | 0.16 | 14 | 27 | 3.5× avg |
| VRTX $515 call | Jul 24, 2026 | 14d | $3.90 | 35.3% | 26 | 0.21 | 1 | 27 | 3.5× avg |
| VRTX $480 call | Jul 17, 2026 | 7d | $11.30 | 28.3% | 8 | 0.63 | 170 | 24 | 2.8× avg |
| VRTX $520 call | Aug 7, 2026 | 28d | $8.07 | 33.4% | 29 | 0.25 | 27 | 20 | 2.6× avg |
| VRTX $490 call | Jul 17, 2026 | 7d | $6.20 | 27.6% | 11 | 0.42 | 407 | 18 | 1.2× avg |
| VRTX $490 call | Aug 21, 2026 | 42d | $22.90 | 35.3% | 52 | 0.51 | 12 | 18 | 1.9× avg |
Ranked by volume at the latest daily snapshot. "vs 30d avg" compares today's volume with the contract's own 30-day average.
The most active VRTX contract today is the $420 put expiring in 70 days, with 450 contracts traded. Calls dominate the most-active list (13 of the top 20), showing where trading interest concentrates.
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VRTX Options FAQ
Which VRTX option contract is most active today?
The most traded VRTX contract is the $420 put expiring Sep 18, 2026, with 450 contracts traded as of Jul 10, 2026.
How does OptiView rank the most active VRTX options?
The table lists the 20 VRTX contracts with the highest volume at the latest daily snapshot, alongside price, implied volatility, delta, open interest, and each contract's volume versus its own 30-day average.
Methodology. IV rank compares the current 30-day at-the-money implied volatility with its highest and lowest values over the past 52 weeks. Max pain is the strike that minimizes the total payout to option holders at expiration. The call and put walls are the strikes carrying the largest call and put open interest across all expirations. Net gamma exposure (GEX) is measured from the dealer perspective. All statistics are derived from delayed OPRA options data.
Options trading involves significant risk, and losses can exceed your initial investment. Always consult a licensed financial professional before making investment decisions. OptiView does not provide financial advice; all figures on this page are descriptive statistics, not recommendations.