Karyopharm Therapeutics Inc. (KPTI) Most Active Options
The 12 most actively traded Karyopharm Therapeutics Inc. (KPTI) option contracts at the latest daily snapshot, ranked by volume. Each row shows the contract's price, implied volatility, delta, open interest, and how today's volume compares with its own 30-day average — click a contract to analyze it in the OptiView platform.
Data as of Oct 12, 2026, 3:55 PM ET · OPRA data 15 minutes delayed · For information only — not investment advice.
Most Active KPTI Contracts
| Contract | Expiration | DTE | Last | IV | IV rank (30d) | Delta | Open interest | Volume | vs 30d avg |
|---|---|---|---|---|---|---|---|---|---|
| KPTI $0.5 put | Nov 20, 2026 | 39d | $0.25 | 368.4% | 100 | -0.27 | 499 | 138 | 1.7× avg |
| KPTI $1 call | Jan 19, 2029 | 830d | $0.40 | 160.5% | 0 | 0.83 | 25 | 26 | 21.9× avg |
| KPTI $1.5 call | Jan 21, 2028 | 466d | $0.40 | 1,005.8% | 0 | 1.00 | 15 | 20 | 16.9× avg |
| KPTI $2.5 call | Feb 19, 2027 | 130d | $0.15 | 3,587.3% | 0 | 1.00 | 185 | 11 | 9.3× avg |
| KPTI $2 call | Jan 21, 2028 | 466d | $0.30 | 2,115.1% | 0 | 1.00 | 60 | 10 | 8.4× avg |
| KPTI $0.5 put | Oct 16, 2026 | 4d | $0.04 | 361.9% | 0 | -0.42 | 224 | 10 | 1.0× avg |
| KPTI $0.5 put | Jan 15, 2027 | 95d | $0.25 | 3,276,025.9% | 100 | 0.00 | 7,158 | 10 | 2.9× avg |
| KPTI $0.5 put | Jan 21, 2028 | 466d | $0.35 | 723,991.5% | 22 | 0.00 | 8,718 | 10 | 2.9× avg |
| KPTI $1 call | Oct 16, 2026 | 4d | $0.05 | 854.4% | 2 | 0.37 | 769 | 9 | 11.7× avg |
| KPTI $2 call | Jan 19, 2029 | 830d | $0.45 | 182.7% | 0 | 0.82 | 123 | 5 | 4.2× avg |
| KPTI $0.5 put | Feb 19, 2027 | 130d | $0.30 | 6,289.8% | 0 | 0.00 | 11,594 | 1 | 0.3× avg |
| KPTI $0.5 call | Nov 20, 2026 | 39d | $0.16 | 3,492.3% | 100 | 1.00 | 2 | 1 | 2.0× avg |
Ranked by volume at the latest daily snapshot. "vs 30d avg" compares today's volume with the contract's own 30-day average.
The most active KPTI contract today is the $0.5 put expiring in 39 days, with 138 contracts traded. Calls dominate the most-active list (7 of the top 12), showing where trading interest concentrates.
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KPTI Options FAQ
Which KPTI option contract is most active today?
The most traded KPTI contract is the $0.5 put expiring Nov 20, 2026, with 138 contracts traded as of Oct 12, 2026.
How does OptiView rank the most active KPTI options?
The table lists the 12 KPTI contracts with the highest volume at the latest daily snapshot, alongside price, implied volatility, delta, open interest, and each contract's volume versus its own 30-day average.
Methodology. IV rank compares the current 30-day at-the-money implied volatility with its highest and lowest values over the past 52 weeks. Max pain is the strike that minimizes the total payout to option holders at expiration. The call and put walls are the strikes carrying the largest call and put open interest across all expirations. Net gamma exposure (GEX) is measured from the dealer perspective. All statistics are derived from delayed OPRA options data.
Options trading involves significant risk, and losses can exceed your initial investment. Always consult a licensed financial professional before making investment decisions. OptiView does not provide financial advice; all figures on this page are descriptive statistics, not recommendations.