Karyopharm Therapeutics Inc. (KPTI) Open Interest
Karyopharm Therapeutics Inc. (KPTI) has 26,397 call contracts and 7,511 put contracts open across all listed expirations — a put/call open interest ratio of 0.28. Open interest counts the contracts currently outstanding at each strike. This page shows where KPTI positioning concentrates, which strikes act as walls, and how the totals have trended over the past year.
Data as of Jul 10, 2026, 8:00 PM ET · OPRA data 15 minutes delayed · For information only — not investment advice.
KPTI Open Interest by Strike
| Total call open interest | 26,397 |
| Total put open interest | 7,511 |
| Put/call OI ratio | 0.28 |
| Open interest rank (31 day) | 100 / 100 |
| Call wall (largest call OI) | $7.5 |
| Put wall (largest put OI) | $7.5 |
| Top volume strike | $10 |
| Volume / OI ratio | 0.01 |
KPTI Open Interest Trend
KPTI total call vs. put open interest, past year.
KPTI put/call open interest ratio, past year.
A put/call open interest ratio of 0.28 means meaningfully more calls than puts are outstanding — a call-heavy, typically bullish positioning profile. In total, 26,397 call contracts and 7,511 put contracts are open across all listed expirations. The put/call OI ratio has fallen from 0.37 in Feb '26 to 0.28 today.
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KPTI Options FAQ
What is KPTI's put/call ratio?
KPTI's put/call open interest ratio is 0.28 as of Jul 10, 2026, with 7,511 put contracts and 26,397 call contracts outstanding.
Which KPTI strikes have the highest open interest?
As of Jul 10, 2026, the largest call open interest sits at $7.5 (the call wall) and the largest put open interest sits at $7.5 (the put wall). Strikes with heavy open interest often act as reference levels because a lot of hedging activity is anchored to them.
Is KPTI open interest unusually high right now?
KPTI's total open interest ranks 100 out of 100 versus the past 31 trading days as of Jul 10, 2026 — toward the top of its recent range, so positioning is unusually heavy.
Methodology. IV rank compares the current 30-day at-the-money implied volatility with its highest and lowest values over the past 52 weeks. Max pain is the strike that minimizes the total payout to option holders at expiration. The call and put walls are the strikes carrying the largest call and put open interest across all expirations. Net gamma exposure (GEX) is measured from the dealer perspective. All statistics are derived from delayed OPRA options data.
Options trading involves significant risk, and losses can exceed your initial investment. Always consult a licensed financial professional before making investment decisions. OptiView does not provide financial advice; all figures on this page are descriptive statistics, not recommendations.